Cytology, Histology and Embryology · MU Plovdiv

52. Umbilical cord. Formation, structure, function. Fetal circulation.

Inside: 5 sections · 6 labelled pictures · 12 flashcards · 7 min

Topic 52 of 55 in the MU Plovdiv syllabus for Cytology, Histology and Embryology (Dental Medicine, Year 1). The free AceMed note covers it in 5 sections, about 950 words (7 min of reading), with 12 flashcards.

In this note

  1. The Umbilical Cord and Embryonic Circulation
  2. The Umbilical Cord: Structure and Function
  3. Embryonic Circulation: The Early Blood Flow Pathways
  4. How the Embryonic Circulatory System Functions
  5. Changes at Birth: Transition to Postnatal Circulation

The Umbilical Cord and Embryonic Circulation

The umbilical cord and embryonic circulation are essential for providing nutrients, oxygen, and waste removal between the developing embryo (and later the fetus) and the mother. This system plays a critical role in sustaining the growing embryo during pregnancy, as the placenta acts as the interface for maternal-fetal exchange.

The Umbilical Cord: Structure and Function

The umbilical cord connects the embryo/fetus to the placenta, providing the necessary pathway for the exchange of gases, nutrients, and waste products. It is an essential structure for the survival and development of the fetus.

Structure of the Umbilical Cord:

  • Length and Appearance: The umbilical cord typically measures about 50 to 60 cm in length and 1-2 cm in diameter at full term, though it can vary. The cord is typically coiled and contains several distinct components.
  • Three Main Vessels:
  • Two Umbilical Arteries: These arteries carry

deoxygenated blood from the fetus to the placenta. They originate from the internal iliac arteries of the fetus and travel along the cord to the placenta.

  • One Umbilical Vein: The vein carries oxygenated, nutrient-rich blood from the placenta back to the fetus. This vein travels through the umbilical cord to the fetus, entering the abdomen and then dividing into smaller vessels within the liver and the inferior vena cava.
  • These three vessels are surrounded by Wharton's jelly, a gelatinous substance that provides structural support to the blood vessels, preventing cord compression and protecting the vessels from external pressure.
  • Other Components:
  • Amniotic Membranes: The cord is enveloped by a layer of amnion (one of the membranes of the amniotic sac), which protects the vessels from mechanical damage.
  • Placental End: At the placental end, the vessels branch out and interconnect with the blood vessels of the placenta. This is where maternal-fetal exchange occurs.

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