Human Physiology · MU Plovdiv

73. General sensation. Somatosensory system – organization and modalities. Mechanisms of thermo- and mechanoreception. Pain sensation. Itch.

Inside: 15 sections · 20 labelled pictures · 37 flashcards · 18 min

Topic 73 of 80 in the MU Plovdiv syllabus for Human Physiology (Medicine, Year 2). The free AceMed note covers it in 13 sections, about 2,505 words (18 min of reading), with 37 flashcards.

In this note

  1. Somatosensory system: general overview. Mechanoreceptors. Thermoreceptors. Nociceptors.
  2. Mechanoreceptors
  3. Types of Mechanoreceptors
  4. Thermoreceptors
  5. Nociceptors
  6. Recap Questions
  7. Somatosensory system: afferent pathways and central processing of information.
  8. Afferent Pathways
  9. Central Processing
  10. Physiology of pain. Primary and secondary pain. Visceral pain. Antinociceptive system.
  11. Visceral Pain
  12. Antinociceptive System
  13. Enkephalins and Endorphins: The Body’s Natural Painkillers

Somatosensory system: general overview. Mechanoreceptors. Thermoreceptors. Nociceptors.

The somatosensory system is responsible for detecting and processing various sensations from the body, including:

  • Touch
  • Pressure
  • Vibration
  • Proprioception (limb position and movement)
  • Temperature
  • Pain

This system relies on a network of specialized sensory receptors, neural pathways, and processing centers in the brain.

The system relies on a 3-neuron relay system. Impulses are carried from receptors via afferent neurons to the dorsal root ganglia where the bodies of the 1st order neurons are located. The 1st order neurons travel through the spinal cord, synapsing to the 2nd order neurons. The 2nd order neurons then convey information to the 3rd order neurons of the thalamus, or the cerebellum. From here, the 3rd order neurons project to the postcentral gyrus (primary somatosensory cortex) of the cortex.

The somatosensory receptors are located in:

  • Skin and mucous membranes. (exteroception)
  • Muscles, tendons and joints. (proprioception)
  • Visceral organs. (interoception)

The 1st order neurons are enveloped in connective tissue together with muscle, tendon, cutaneous cells or hair follicles. The tissue capsule + afferent terminal form a “somatosensory receptor”.

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