Occupational Diseases and Toxicology · MU Plovdiv

12. Occupational intoxications with non-organic lead compound (chronic saturnism) - etiology, pathogenesis, clinical manifestations, diagnosis, treatment, medical expertise.

Inside: 7 sections · 1 table · 16 flashcards · 5 min

Topic 12 of 60 in the MU Plovdiv syllabus for Occupational Diseases and Toxicology (Medicine, Year 3). The free AceMed note covers it in 7 sections, about 705 words (5 min of reading), with 16 flashcards.

In this note

  1. Introduction
  2. Etiology and sources
  3. Pathogenesis
  4. Clinical manifestations
  5. Diagnosis
  6. Treatment and prevention
  7. Medical expertise

Introduction

This topic covers chronic saturnism, the long-term poisoning caused by inorganic lead compounds absorbed at work. It covers the sources and routes of exposure, how lead acts on the body, the nervous, gastrointestinal, haematological and renal effects, how the disease is diagnosed and treated, and how occupational medical expertise is applied.

Etiology and sources

Chronic lead poisoning is caused by repeated exposure to inorganic lead compounds, mainly lead acetate, lead chloride and lead nitrate, as well as metallic lead and lead oxides in dust and fume. Lead is a persistent pollutant: it does not break down, it accumulates in dust, soil and old materials, and it can remain a hazard in a workplace for many years after production has stopped.

  • Storage battery production, recycling and repair
  • Soldering, cable and metal smelting, and lead refining
  • Paint manufacture, painting and removal of old lead paint
  • Ceramic glazes and pottery, printing inks, and glass
  • Plastics (lead stabilisers in PVC) and ammunition production

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