SIEWERT-STEIN CLASSIFICATION
a system of anatomical classification used for adenocarcinomas of the esophagogastric junction.
Type I- 7cm above anatomical cardia/Gastroesophageal junction. Seen in Adenocarcinoma of distal esophagus.
Type II – 3-2cm above, 1cm below - II- Known as true junctional carcinoma.
Type III- 1cm above, 2 cm below -II- Known as subcardinal carcinoma.
What does “Barrett’s Esophagus” mean?
Barret’s Esophagus is the condition in which the normal squamous epithelium of the distal esophagus is replaced with columnar epithelium in response to chronic exposure to gastric juice.
Three gross patterns of growth of esophageal cancer are commonly seen. Which are they?
Three gross patterns of growth are commonly seen:
- I. Ulcerating type: well-defined ulcer with raised, irregular edges.
- II. Fungating type: Has a large intraluminal component with an irregular surface
- III. Infiltrative type: Has extensive intramural growth, often circumferential, with minimal ulceration
There are two major histological types of esophageal cancer. Which are they?
The two major histological types of esophageal cancer are:
- I. Squamous cell carcinoma: Squamous cell carcinomas arise from the squamous mucosa that is native to the esophagus.
- II. Adenocarcinoma. Esophageal adenocarcinoma arise from one of the three sites:
- i. Submucosal glands of the esophagus,
- ii. Heterotopic islands of columnar epithelium
- iii. Malignant degeneration of metaplastic columnar epithelium (Barrett’s Esophagus).