Worldwide, which is the most common cancer?
- Worldwide, gastric cancer is the 4TH most common cancer and the 2ND leading cause of cancer death.
In which gender stomach cancer is more common?
- Stomach cancer is universally more common in men than women (ratio 2:1)
Which stomach cancers have worse prognosis, based on their localization?
- In general, proximally placed tumours have a worse prognosis than those sited distally.
What is the definition of “early gastric cancer”?
- “Early gastric cancer“ is the tumor that is confined to the gastric mucosa & submucosa.
What is the definition of “advanced gastric cancer”?
- “Advanced gastric cancer” is tumor with deeper invasion than stomach mucosa & submucosa.
Which are the variations in the gross appearance of advanced gastric cancers?
- Polypoid fungating tumor (with a nodular polypoid surface with superficial ulceration)
- Ulcerating cancer (may look like a benign gastric ulcer)
- Superficial spreading carcinoma (it is diffusely infiltrative over a wide are).
What is the definition of “Linitis plastic ” carcinoma?
- Linitis plastic stomach carcinoma is a subgroup of diffusely infiltrative cancer
- Characterized by extensive infiltration of the submucosa and muscular layers with a marked fibroblastic/desmoplastic reaction around columns of malignant cells.
Which is the most definitive diagnostic method in gastric neoplasm?
- Fiberoptic endoscopy is the most definitive diagnostic method when gastric neoplasm is suspected.
How can be made differentiation of benign from malignant gastric ulcers?
STAGING
CT-PET & MRI
- Differentiation of benign from malignant gastric ulcers can be made definitively ONLY with gastric biopsy.
- Accuracy of diagnosis can exceed 95% if multiple biopsy specimens are obtained.