Which is the most common localisation of pancreatic adenocarcinoma?
- The pancreatic head → seventy percent of tumour occurs in pancreatic head.
What does “Courvoisier’s sign” mean?
in Pts w Painless obstructive Jaundice. due to pancreatic head cancer
- Palpable enlarged gallbladder.
- Two-thirds of patients with pancreatic cancer and obstructive jaundice exemplify
Courvoisier’s law which states that this finding indicates a malignant distal biliary obstruction.
What is the name of one-stage operation of choice for patients with pancreatic cancer?
Resect:
- Head of Pancreas
- Duodenum
- Gall bladder
- Distal bile duct
- Pylorus
Then do reconstruction
➥ The one stage operation of choice for patients with pancreatic cancer localised to the head, neck, or uncinate process of the pancreas is named Whipple’s operation (pancreaticoduodenectomy).
What does “Virchow’s gland” mean?
➥ Virchow’s gland is palpable, hard left supraclavicular lymph node
Suggests Metastatic spread of Gastric, Pancreatic cancer
Functional pancreatic neuroendocrine tumors
Which are the functional tumours of endocrine pancreas?
➥ Functional islet cell tumour (tumour of endocrine pancreas) is
- Insulinoma
- Glucagonoma
- Gastrinoma
- VIPoma
- Somatostatinoma.
Which is the most common neoplasm of the endocrine pancreas?
- Insulinoma → is the common neoplasm of the endocrine pancreas (constitutes about 70% of all pancreatic endocrine tumours).
What does Zollinger- Ellison syndrome mean?
➥ “Zollinger- Ellison syndrome” means→
- Severe peptic ulceration, often multiple, with a progressive and complicated course and sometimes found in the distal rather than the proximal duodenum.
- The excess secretion of gastrin by gastrinoma stimulates an excess production of gastric acid and leads to the development of the Zollinger- Ellison syndrome.