Internal Medicine (Practical) · MU Sofia

12.Symptoms and Syndromes of Cardiovascular Disease

Covers the main symptoms of cardiovascular disease, including chest pain, palpitations, dyspnoea, fatigue, syncope and oedema, with their characteristic features and causes. It then moves to common syndromes such as ischaemic heart disease, valvular disease, arrhythmias and heart failure, and closes with pericardial diseases. Notable additions are the Beck's triad for cardiac tamponade and the description of orthopnoea and paroxysmal nocturnal dyspnoea.

Inside: 4 sections · 9 labelled pictures · 16 flashcards · 4 min

Topic 11 of 30 in the MU Sofia syllabus for Internal Medicine (Practical) (Medicine, Year 3). The free AceMed note covers it in 4 sections, about 585 words (4 min of reading), with 16 flashcards.

In this note

  1. Symptoms and Syndromes of Cardiovascular Disease
  2. Main Symptoms
  3. Common Syndromes
  4. Pericardial Diseases

Main Symptoms

1. Chest Pain

  • Important symptom for many cardiac diseases (especially ischemic heart disease).
  • Character:
  • Pressure-like, squeezing, burning, or stabbing sensation.
  • Radiation:
  • Can radiate to the left arm, jaw, neck, back, or epigastrium.
  • Timing:
  • Stable angina: Occurs during exertion, relieved by rest or nitroglycerin.
  • Unstable angina / Myocardial infarction: Occurs at rest, more severe, lasts longer (>20 minutes).
  • Associated symptoms:
  • Sweating, nausea, palpitations, shortness of breath.

Always assess: nature of pain, duration, triggers, relieving factors.

2. Palpitations

  • Awareness of abnormal heartbeat: either too fast, too slow, or irregular.
  • Described by patients as:
  • Fluttering
  • Pounding
  • Skipping beats
  • Possible causes:
  • Arrhythmias (e.g., atrial fibrillation, supraventricular tachycardia)
  • Anxiety, hyperthyroidism, anemia.
  • Important to ask:
  • Onset (sudden or gradual), duration, associated symptoms (e.g., syncope, chest pain).

3. Dyspnea

  • Shortness of breath, often cardiac in origin when no lung disease present.
  • Types:
  • Orthopnea:
  • Difficulty breathing while lying flat.
  • Seen in left-sided heart failure (pulmonary congestion).
  • Patient often uses multiple pillows to sleep.
  • Paroxysmal Nocturnal Dyspnea (PND):
  • Sudden severe breathlessness at night.
  • Patient wakes up gasping for air, needs to sit up.
  • Caused by redistribution of fluids into lungs when lying down.

Dyspnea on exertion is an early symptom of heart failure.

4. Fatigue

  • Common but nonspecific symptom.
  • Seen in:
  • Heart failure (reduced cardiac output → ↓ oxygen supply to muscles).
  • Valvular heart diseases (e.g., aortic stenosis, mitral regurgitation).
  • Worse with exertion, improves with rest.

5. Dizziness/Syncope

  • Syncope = transient loss of consciousness due to decreased cerebral perfusion.
  • Causes:
  • Arrhythmias (e.g., bradycardia, tachyarrhythmias)
  • Aortic stenosis (fixed cardiac output)
  • Hypertrophic obstructive cardiomyopathy
  • Severe hypotension
  • Important points:
  • Circumstances (at rest, exertion, emotional stress)
  • Warning signs (palpitations, chest pain)
  • Duration of unconsciousness
  • Recovery (spontaneous, full recovery)

6. Edema

  • Swelling most often seen in:
  • Lower legs and ankles (dependent edema)
  • Sacrum (especially in bedridden patients)
  • Mechanism:
  • Right-sided heart failure → increased venous pressure → fluid leakage into tissues.
  • Features:
  • Pitting on pressure.
  • Worse in evening (gravity-related).

Edema can also occur in nephrotic syndrome, liver cirrhosis — important to differentiate.

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