Physics · MU Sofia

41. Effect of ionizing radiation on human organism.

Explains how ionising radiation affects the human body, starting with the dosimetric quantities used to measure exposure: absorbed, equivalent and effective dose, along with their power counterparts and units. It then surveys natural and technogenic sources, external and internal irradiation, and deterministic versus stochastic biological effects with cellular mechanisms. It closes with radiation protection principles, including ALARA, time, distance and shielding. A diagram of biological effects and several dose formulas are included.

Inside: 7 sections · 6 labelled pictures · 9 flashcards · 2 min

Topic 42 of 42 in the MU Sofia syllabus for Physics (Medicine, Year 1). The free AceMed note covers it in 7 sections, about 329 words (2 min of reading), with 9 flashcards.

In this note

  1. Effect of Ionizing Radiation on the Human Organism
  2. Introduction
  3. Dosimetric Quantities
  4. Sources of Ionizing Radiation
  5. Types of Irradiation
  6. Biological Effects of Ionizing Radiation
  7. Radiation Protection Principles

Introduction

Ionizing radiation interacts with human tissues by depositing energy, leading to ionization and excitation of atoms and molecules. These interactions can damage DNA and cells, causing both immediate and long-term health effects. Dosimetry provides the framework for quantifying exposure and risk.

Dosimetric Quantities

  • Absorbed Dose (D):
  • Energy imparted by radiation per unit mass of tissue.
  • Formula:
  • Unit: gray (Gy).
  • Power of Absorbed Dose (PD):
  • Rate of energy deposition in tissue.
  • Unit: Gy/s.
  • Exposure (X):
  • Ionization produced in air by X-rays or γ-rays.
  • Unit: coulombs per kilogram (C/kg).
  • Power of Exposure (Px):
  • Rate of exposure delivery.
  • Unit: (C/kg)/s.
  • Equivalent Dose (H):
  • Accounts for type of radiation.
  • Formula:
  • Unit: sievert (Sv).
  • WR: radiation weighting factor (e.g., 1 for γ, β; 20 for α).
  • Power of Equivalent Dose (PH):
  • Rate at which equivalent dose is delivered.
  • Unit: Sv/s.
  • Effective Dose (E):
  • Considers sensitivity of tissues (tissue weighting factor WT ).
  • Formula:
  • Unit: sievert (Sv).

Sources of Ionizing Radiation

Natural Sources

  • Cosmic radiation (higher at altitude).
  • Terrestrial radiation from soil, rocks.
  • Radon gas (largest contributor to natural background).
  • Naturally radioactive isotopes (K-40, C-14).

Technogenic (Artificial) Sources

  • Medical: X-ray imaging, CT, nuclear medicine, radiotherapy.
  • Industrial: nuclear power, radiography, material testing.
  • Fallout: from past nuclear tests, accidents.
  • Consumer products: luminous dials, smoke detectors.

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