Physiology · MU Pleven

RELATION BETWEEN MUSCLE LENGTH, TENSION AND VELOCITY OF CONTRACTION

Explains how the length of a muscle before activation affects the strength and speed of its contraction, and how load slows shortening until it stops at maximum force. It then covers the energy sources that restore ATP, namely phosphocreatine, glycogen glycolysis and oxidative metabolism, and closes with muscle fatigue and its causes. A diagram accompanies the length-tension discussion.

Inside: 4 sections · 1 labelled picture · 20 flashcards · 2 min

Topic 10 of 17 in the MU Pleven syllabus for Physiology (Medicine, Year 2). The free AceMed note covers it in 4 sections, about 291 words (2 min of reading), with 20 flashcards.

In this note

  1. TOPIC 10. RELATION BETWEEN MUSCLE LENGTH, TENSION AND VELOCITY OF CONTRACTION. SOURCES OF ENERGY FOR MUSCLE CONTRACTION. MUSCLE FATIGUE.
  2. RELATION BETWEEN MUSCLE LENGTH, TENSION AND VELOCITY OF CONTRACTION
  3. SOURCES OF ENERGY FOR MUSCLE CONTRACTION
  4. MUSCLE FATIGUE

RELATION BETWEEN MUSCLE LENGTH, TENSION AND VELOCITY OF CONTRACTION

MAXIMUM STRENGTH OF CONTRACTION → when muscle has the resting length before activation

VELOCITY OF MUSCLE CONTRACTION → maximal at the resting length.

  • A muscle contracts extremely rapidly when no load is applied.
  • When load is applied the velocity of contraction decreases and becomes zero if this load equals the maximum force that the muscle can exert.

SOURCES OF ENERGY FOR MUSCLE CONTRACTION

  • PHOSPHOCREATINE → used to reconstitute the ATP
  • Carries a high-energy phosphate bond similar to the bonds of ATP → has a slightly higher amount of free energy than that of each ATP bond.
  • GLYCOLYSIS OF GLYCOGEN (previously stored in muscle cells) → used to reconstitute both ATP and phosphocreatine
  • Rapid enzymatic breakdown of the glycogen to pyruvic acid and lactic acid liberates energy that is used to convert ADP to ATP; the ATP can then be used directly to energize additional muscle contraction and also to re-form the stores of phosphocreatine.
  • OXIDATIVE METABOLISM → combining oxygen with the end products of glycolysis and with various other cellular foodstuffs to liberate ATP
  • More than 95 % of all energy used by the muscles for sustained, long-term contraction is derived from oxidative metabolism.

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