20. Classification of lipids. Hydrolyzable lipids-examples. Chemical aspects of biological oxidation of fats and oils. Phospholipids – types and biological significance.
Topic 20 of 26 in the MU Plovdiv syllabus for Chemistry (Medicine, Year 1). The free AceMed note covers it in 8 sections, about 1,372 words (10 min of reading), with 21 flashcards.
In this note
Lipids - definition and classifications.
Ketoacyl lipids.
Long chain fatty acids.
Fats - structure and properties.
Oxidation.
Saponification of fats.
Glycerophospholipids - structure, types and biological significance.
Sphingosine and sphingophospholipids - structure and biological significance.
Lipids - definition and classifications.
Lipids are a diverse group of biomolecules united more by their physical properties (like being oily and water-fearing) than by their chemical structures. They play crucial roles in our bodies, from building cell walls to storing energy.
classifications:
By Structure:
Simple Lipids: Think fats and waxes - they're just fatty acids hanging out with an alcohol (fats) or a long hydrocarbon chain (waxes).
Complex Lipids: These are more intricate, like phospholipids (key players in cell membranes) and glycolipids (involved in cell signaling).
Derived Lipids: Fatty acids themselves, along with hormones and steroids (like cholesterol), fall into this category.
By Reaction with Water:
Saponifiable Lipids: These can be broken down with bases (like lye) into soap - think fatty acids and triglycerides (fats).
Non-saponifiable Lipids: Water and soap won't touch these - they include sterols (like cholesterol) and fat-soluble vitamins (A, D, E, and K).
By Biosynthesis (How They're Made):
Fatty Acyl Group: This group includes fatty acids, the building blocks for many other lipids, as well as fats, phospholipids, glycolipids, and even waxes.
Isoprene: This building block forms the backbone of terpenes (found in essential oils), fat-soluble vitamins, and steroids.
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