Shock
Written by Rhiana Devadasan
18) Shock - types, pathophysiology, basic principles of treatment.
Shock = physiological state characterized by systemic reduction in tissue perfusion resulting in decreased tissue oxygen delivery. (i.e. an inadequacy of the circulatory system to provide for the body)
General Pathophysiology (common to all types of shock)
- ↓BF to tissues
- Whole body circulatory failure
- Cellular damage due to hypoxia
- Multiple organ failure
BF to tissues is predominantly dependent on BLOOD PRESSURE.
FACTORS DETERMINING BLOOD PRESSURE ARE:
- Blood Vessel's Resistance to Blood Flow - dependent on vessel diameter & length
- Cardiac output (HR x SV)
Stages of Shock:
- Compensated
Body can compensate & maintain tissue perfusion. This is achieved by BLOOD SHUNTING (direct connection bet. venous & arterial blood w/o oxygenating. Precapillary sphincters close), ↑HR, ↑Strength of contractions, ↑ respiratory function, bronchodilation, etc.
- Progressive/Uncompensated
Begins to lose compensation = inadequate perfusion begins. ↓CO, ↑HR, ↑thrombus formation, BF stagnates
- Irreversible
Cell & tissue damage and Organ failure.