General and Operative Surgery · MU Plovdiv

42. Blood transfusion – history, ABO system and Rh factor / Rh/. Determination of blood groups. Indications and contraindications for blood transfusion. Blood products.

Inside: 9 sections · 5 labelled pictures · 1 table · 16 min

Topic 42 of 77 in the MU Plovdiv syllabus for General and Operative Surgery (Medicine, Year 3). The free AceMed note covers it in 9 sections, about 2,310 words (16 min of reading).

In this note

  1. Blood Transfusion
  2. HISTORY
  3. BLOOD GROUPS
  4. Choosing the right Donor:
  5. BLOOD TRANSFUSIONS
  6. INDICATIONS
  7. CONTRAINDICATIONS:
  8. MISTAKES AND COMPLICATIONS:
  9. BLOOD PRODUCTS

Blood Transfusion

Written by Rhiana Devadasan

40) Blood transfusion - history, ABO and Rhesus system (Rh). Blood groups.

41) Blood transfusion - indications & contraindications. Mistakes & complications.

42) Blood transfusion - indications and contraindications for blood transfusion. Blood products.

Blood transfusion = the transfer of blood or blood components (e.g. plasma, RBCs, platelets) from one individual (called the donor) to another (called the recipient) intravenously.

HISTORY

  • 1665 – Richard Lower – first successful animal-animal blood transfusion (one dog to another).
  • 1667 – Denis and Emmerez – transfused blood of a lamb into a human (animal to human). The woman underwent a hemolytic transfusion reaction (indicated by black urine) but survived.
  • 1828 – first successful transfusion.
  • 1900 – Landsteiner described ABO – he found that serum from some individuals could agglutinate / haemolyse the RBCs of certain other individuals.
  • 1902 – Sturli & DeCastello – described the fourth blood group, the AB group.
  • 1916 – first use of blood storage.
  • 1939 – Levine described the Rh factor.
  • 1940 – Landsteiner & Wiener – described Rh blood type, which lead to a dramatic decrease in the incidence of haemolytic disease of the new-born.

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