Biophysics · MU Sofia

15. Membrane transport 1: subject and importance of membrane transport. Types of transport (classification). Free diffusion of non-charged particles - first and second Fick's laws. The Stokes-Einstein equation

Introduces membrane transport as the passage of small molecules and ions across membranes, outlining its roles in cell volume regulation, nutrient uptake and ion gradients, and why transport faults underlie disease. It then classifies transport into passive types (diffusion, facilitated diffusion, osmosis) and active types (protein pumps, endocytosis, exocytosis). Fick's second law is stated in words, with the rest of the topic's formulas shown only in pictures.

Inside: 1 section · 4 labelled pictures · 12 flashcards · 1 min

Topic 15 of 26 in the MU Sofia syllabus for Biophysics (Dental Medicine, Year 2). The free AceMed note covers it in 1 section, about 218 words (1 min of reading), with 12 flashcards.

In this note

  1. Membrane transport 1

Membrane transport 1

Subject and importance of the membrane transport. Types of transport (classification). Free diffusion of non-charged particles - first and second Fick’s laws. The Stokes-Einstein equation.

Definition and functions of the membrane transport:

  • Transport: Processes of passing through membrane of small molecules and ions. Usually it’s a highly selectable process.

Functions:

  • Regulation of the cells volume
  • Imports substances necessary for energy & growth in cell
  • Maintains the ion gradients & transforms energy

Importance:

  • Faults in transport are cause for many diseases.
  • Some kind of drugs can restore the normal cells function, changing due to membrane transport.

Types of cellular transport:

PASSIVE TRANSPORT:

  • Cell does not use energy
  • Molecules move randomly
  • Molecules spread out from an area of high concentration to an area of low concentration

There are 3 types of passive transport:

  1. 1. Diffusion
  2. 2. Facilitated diffusion - diffusion with help of transport proteins
  3. 3. Osmosis - diffusion of water

ACTIVE TRANSPORT:

  • Cell does use energy
  • Actively moves molecules to where they are needed
  • Movement from area of low concentration to area with high concentration

There are 3 types of active transport.

  1. 1. Protein pumps
  2. 2. Endocytosis
  3. 3. Exocytosis

Fick’s 2nd law states that the change in concentration with time in a particular region is proportional to the change in the concentration gradient at that point in the system.

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