Chemistry · MU Sofia

16.1. Lipids

Covers the definition of lipids and their classification by structure, by reaction with water and by biosynthesis, then long chain fatty acids with stearic, oleic and palmitic acid examples. It goes on to fats and glycerophospholipids, their amphipathic behaviour and membrane bilayers, beta-oxidation, saponification, and sphingosine and sphingophospholipids, with their roles in myelin and cell signalling.

Inside: 8 sections · 11 labelled pictures · 21 flashcards · 10 min

Topic 40 of 42 in the MU Sofia syllabus for Chemistry (Dental Medicine, Year 1). The free AceMed note covers it in 8 sections, about 1,373 words (10 min of reading), with 21 flashcards.

In this note

  1. Lipids - definition and classifications.
  2. Ketoacyl lipids.
  3. Long chain fatty acids.
  4. Fats - structure and properties.
  5. Oxidation.
  6. Saponification of fats.
  7. Glycerophospholipids - structure, types and biological significance.
  8. Sphingosine and sphingophospholipids - structure and biological significance.

Lipids - definition and classifications.

  • Lipids are a diverse group of biomolecules united more by their physical properties (like being oily and water-fearing) than by their chemical structures. They play crucial roles in our bodies, from building cell walls to storing energy.
  • classifications:
  • By Structure:
  • Simple Lipids: Think fats and waxes - they're just fatty acids hanging out with an alcohol (fats) or a long hydrocarbon chain (waxes).
  • Complex Lipids: These are more intricate, like phospholipids (key players in cell membranes) and glycolipids (involved in cell signaling).
  • Derived Lipids: Fatty acids themselves, along with hormones and steroids (like cholesterol), fall into this category.
  • By Reaction with Water:
  • Saponifiable Lipids: These can be broken down with bases (like lye) into soap - think fatty acids and triglycerides (fats).
  • Non-saponifiable Lipids: Water and soap won't touch these - they include sterols (like cholesterol) and fat-soluble vitamins (A, D, E, and K).
  • By Biosynthesis (How They're Made):
  • Fatty Acyl Group: This group includes fatty acids, the building blocks for many other lipids, as well as fats, phospholipids, glycolipids, and even waxes.
  • Isoprene: This building block forms the backbone of terpenes (found in essential oils), fat-soluble vitamins, and steroids.

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