Slide 30. Pseudounipolar neurons of the spinal ganglion, H&E
Explains the spinal dorsal root ganglion slide stained with H&E, where pink cytoplasm and blue-purple nuclei mark the cell bodies of pseudounipolar sensory neurons whose single process splits into peripheral and central branches. It lists the features to look for, including the dense connective tissue capsule, clusters of large round neurons, satellite cells around each one and nerve fibre bundles between them. It also contrasts the picture with an autonomic ganglion, whose neurons are multipolar, smaller and more scattered, and points back to the earlier theory on neuron types.
Inside: 1 section · 1 min
Topic 119 of 127 in the MU Sofia syllabus for Cytology (Dental Medicine, Year 1). The free AceMed note covers it in 1 section, about 122 words (1 min of reading).
In this note
Introduction
Introduction
The spinal (dorsal root) ganglion holds the cell bodies of the pseudounipolar sensory neurons. Each has one process that splits in a T: one branch goes to the periphery and one into the spinal cord.
Stain
H&E: cytoplasm pink, nuclei blue-purple.
How to recognise it
A capsule of dense connective tissue around the ganglion.
Clusters of large, round cell bodies of different sizes, mostly near the edge.
No processes are visible on the cell bodies, and there are no synapses in the ganglion.
A ring of small satellite cells around each neuron.
Bundles of nerve fibres between the groups of cells.
Don't confuse it with: an autonomic ganglion, whose neurons are multipolar, smaller and more scattered.
Theory: topic 64 (types of neurons).
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