Obstetrics and Gynaecology · MU Sofia

39. Shock in obstetrics. Amniotic fluid embolism. Coagulopathies in obstetrics

Covers shock in obstetrics, with a table of its types (haemorrhagic, septic, obstructive or cardiogenic, neurogenic and anaphylactic) and their obstetric causes, followed by management steps and the shock index. Next it describes amniotic fluid embolism: its rarity, its anaphylactoid nature, clinical features, diagnosis by exclusion and supportive treatment including perimortem caesarean. It ends with coagulopathies, covering DIC causes, diagnostic findings, and replacement therapy.

Inside: 3 sections · 1 table · 16 flashcards · 2 min

Topic 39 of 61 in the MU Sofia syllabus for Obstetrics and Gynaecology (Dental Medicine, Year 4). The free AceMed note covers it in 3 sections, about 306 words (2 min of reading), with 16 flashcards.

In this note

  1. Shock in obstetrics
  2. Amniotic fluid embolism
  3. Coagulopathies in obstetrics

Shock in obstetrics

Shock is failure of tissue perfusion. Pregnant women compensate well (large blood volume), so tachycardia and hypotension appear late, after losing 30–40% of the blood volume.

Management

  • Call for help; left lateral tilt (relieves caval compression); airway, high-flow oxygen.
  • Two large IV lines, warmed crystalloid, then blood early (O-negative if needed), FFP, platelets and fibrinogen in a massive transfusion protocol.
  • Find and stop the cause (surgery, uterotonics, antibiotics); catheter and hourly urine output; ICU.
  • Shock index (heart rate ÷ systolic BP) > 0.9–1 suggests serious blood loss.

Amniotic fluid embolism

A rare (≈ 2–6 per 100,000) but often fatal reaction when amniotic fluid and fetal cells enter the maternal circulation, usually in labour or just after birth. It is an anaphylactoid reaction, not simply a mechanical block.

  • Sudden breathlessness, hypoxia, hypotension and collapse, seizures, cardiac arrest, followed by DIC with massive bleeding.
  • A clinical diagnosis after excluding PE, sepsis, anaphylaxis and haemorrhage.
  • Treatment is supportive: resuscitation, ventilation, inotropes, perimortem caesarean within 4–5 minutes of arrest if undelivered (also helps the mother), correct coagulopathy.

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