Physiology · MU Sofia

82. Somatosensory system: general overview. Mechanoreceptors. Thermoreceptors. Nociceptors.

Covers the somatosensory system's three-neuron relay from receptors to the cortex, then the receptor types for touch, proprioception, temperature and pain. Mechanoreceptors in skin, muscle, tendon and joint are compared by adaptation and receptive field. Thermoreceptors are explained through TRPM8 cold sensing and menthol, and nociceptors are classified by stimulus with the fibres carrying pain. A set of recap questions closes the note.

Inside: 6 sections · 8 labelled pictures · 17 flashcards · 7 min

Topic 81 of 104 in the MU Sofia syllabus for Physiology (Dental Medicine, Year 2). The free AceMed note covers it in 6 sections, about 959 words (7 min of reading), with 17 flashcards.

In this note

  1. Somatosensory system: general overview. Mechanoreceptors. Thermoreceptors. Nociceptors.
  2. Mechanoreceptors
  3. Types of Mechanoreceptors
  4. Thermoreceptors
  5. Nociceptors
  6. Recap Questions

Somatosensory system: general overview. Mechanoreceptors. Thermoreceptors. Nociceptors.

The somatosensory system is responsible for detecting and processing various sensations from the body, including:

  • Touch
  • Pressure
  • Vibration
  • Proprioception (limb position and movement)
  • Temperature
  • Pain

This system relies on a network of specialized sensory receptors, neural pathways, and processing centers in the brain.

The system relies on a 3-neuron relay system. Impulses are carried from receptors via afferent neurons to the dorsal root ganglia where the bodies of the 1st order neurons are located. The 1st order neurons travel through the spinal cord, synapsing to the 2nd order neurons. The 2nd order neurons then convey information to the 3rd order neurons of the thalamus, or the cerebellum. From here, the 3rd order neurons project to the postcentral gyrus (primary somatosensory cortex) of the cortex.

The somatosensory receptors are located in:

  • Skin and mucous membranes. (exteroception)
  • Muscles, tendons and joints. (proprioception)
  • Visceral organs. (interoception)

The 1st order neurons are enveloped in connective tissue together with muscle, tendon, cutaneous cells or hair follicles. The tissue capsule + afferent terminal form a “somatosensory receptor”.

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