Clinical Pathology · MU Sofia

80. Intestinal obstruction (ileus) – types. Mesenteric thrombosis. Complications.

Covers mechanical and paralytic types of intestinal obstruction, including the causes of each, the share of mechanical cases due to hernias, adhesions, intussusception and volvulus, and Hirschsprung disease as a neonatal cause. It then describes mesenteric thrombosis: which vessels clot, the common predisposing conditions, typical symptoms, and bowel ischaemia with gangrene. A gross photograph of haemorrhagic infarction of the small bowel is included.

Inside: 1 section · 2 labelled pictures · 14 flashcards · 1 min

Topic 80 of 138 in the MU Sofia syllabus for Clinical Pathology (Medicine, Year 4). The free AceMed note covers it in 1 section, about 245 words (1 min of reading), with 14 flashcards.

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  1. Intestinal obstruction (ileus) types. Mesenteric thrombosis. Complications

Intestinal obstruction (ileus) types. Mesenteric thrombosis. Complications

Intestinal obstruction

Collectively, hernias, intestinal adhesions, intussusception and volvulus account for 80% of all mechanical obstructions, while tumours and infarction are generally the rest. Clinical picture includes pain, distention, vomiting and constipation. Surgery is usually required.

Remember: ileus is either mechanical, with a physical block (hernia, adhesions, volvulus, intussusception, tumour), or paralytic (adynamic), where peristalsis stops without a block, e.g. after abdominal surgery, in peritonitis, hypokalaemia or with opioids. Strangulation of a mechanical obstruction cuts the blood supply and leads to infarction.

Hirschsprung disease (1 in 5000 births) is a congenital disorder where the enteric neural plexus fails to properly develop causing loss of submucosal plexus and myenteric plexus meaning peristalsis is absent. Along with congenital hernias, this is one of the more common intestinal obstructions in newborns.

Mesenteric thrombosis

This is a blood clot in one of the veins draining or arteries supplying the intestines, it can affect the splenic vein, or superior or inferior mesenteric vessels. Clots to these veins can occur due to abdominal injury, clotting disorders, inflammatory bowel diseases, pancreatitis, liver cirrhosis and tumours.

Symptoms will include abdominal pain, bloating, diarrhea, vomiting and possibly fever with bloody stools.

Where we see an arterial blockage we will see ischemia and gangrene of the bowel wall.

Gross: haemorrhagic infarction of the small bowel (here from strangulation in an inguinal hernia; mesenteric thrombosis looks the same). The wall is swollen and dusky purple-red.

Image: “Haem infarction, small bowel” by Narraburra, CC0, via Wikimedia Commons.

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