Cytology · MU Sofia

12. Chemical composition of the cell. Basic chemical compounds. Carbohydrates and lipds.

Covers the main elements and organic molecule classes of the cell, with a focus on carbohydrates and lipids. The lipid section describes phospholipids and their bilayer, plus glycolipids, fatty acids, phosphoglycerides, sphingolipids and sterols. The carbohydrate section explains monosaccharides, disaccharides, glycogen and starch, followed by the PAS staining method and four key functions of carbohydrates, including energy storage, protein sparing and lipid metabolism.

Inside: 4 sections · 15 flashcards · 8 min

Topic 12 of 97 in the MU Sofia syllabus for Cytology (Medicine, Year 1). The free AceMed note covers it in 4 sections, about 1,181 words (8 min of reading), with 15 flashcards.

In this note

  1. Introduction
  2. Major Classes of Organic Biomolecules
  3. Visualization of Carbohydrates in Cells
  4. Importance of Carbohydrates

Introduction

Basic Chemical Composition of the Cell

The cell is the fundamental unit of life, and like all matter, it's composed of various chemical elements. While numerous elements are found in trace amounts, a select few constitute the bulk of a cell's mass. These primary elements are hydrogen, oxygen, nitrogen, carbon, sulfur, and phosphorus. The most abundant compound found in cells is water, comprising approximately 99% of the cell's volume. The remaining 1% consists of a complex array of both organic and inorganic molecules, with proteins generally outnumbering DNA in terms of quantity within a cell. It's worth noting that any abnormalities in these biomolecules, the chemical reactions they participate in, or the intricate biochemical pathways they're involved in can often lead to various diseases.

Major Classes of Organic Biomolecules

The primary elements combine to form four major classes of organic biomolecules that are essential for life: nucleic acids, proteins, lipids, and carbohydrates.

  • Nucleic Acids: Nucleic acids, namely DNA (deoxyribonucleic acid) and RNA (ribonucleic acid), are macromolecules that carry genetic information. These complex molecules are composed of chains of simpler units called nucleotides. Each nucleotide consists of three components: a five-carbon sugar, a phosphate group, and a nitrogenous base. The type of sugar differentiates DNA and RNA: DNA contains deoxyribose, while RNA contains ribose. The phosphate groups link the sugar molecules together, forming a sugar-phosphate backbone, while the nitrogenous bases protrude from this backbone. Nucleic acids can exist as single strands or double strands, with the latter being characteristic of DNA, where two strands are held together by hydrogen bonds between complementary nitrogenous bases.

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