Inspiratory Dyspnea
1. Definition: Inspiratory dyspnea is a type of breathing difficulty characterized by laboured inhalation. It occurs when the airway diameter narrows and airflow resistance increases during inspiration, typically due to an upper airway obstruction- larynx or trachea. It is commonly associated with inspiratory stridor.
2. Etiopathogenesis
- Congenital: Laryngomalacia (most common in infants), subglottic stenosis, web.
- Inflammatory/Infectious: Epiglottitis, Laryngotracheobronchitis (Croup), peritonsillar or retropharyngeal abscess, diphtheria.
- Traumatic: Foreign body aspiration, laryngeal fractures, post-intubation edema.
- Neoplastic: Laryngeal papillomatosis (benign), Squamous cell carcinoma (malignant).
- Neurological: Bilateral vocal cord paralysis (eg, post-thyroidectomy).
- Allergic: Angioedema (Quincke's edema).
During inspiration:
Negative pressure is created inside the airway.
If the airway is narrowed, this negative pressure causes further collapse.
Airflow becomes turbulent → produces stridor.
👉 Therefore, inspiratory dyspnea indicates upper airway obstruction
3. Classification of Airway Obstruction
- Stage I (Compensated): Dyspnea occurs only during physical exertion. Patient anxious but stable Oxygenation adequate
- Stage II (Partial Decompensation): Dyspnea at rest; use of accessory muscles begins.
- Stage III (Decompensated): Severe dyspnea, marked stridor, suprasternal and intercostal retractions, anxiety, and cyanosis.
- Stage IV (Asphyxia): Terminal stage; bradycardia, gasping, loss of consciousness, and respiratory arrest.
4. Clinical Picture
The hallmark of inspiratory dyspnea is Stridor —a high-pitched, musical sound produced by turbulent airflow through a narrowed upper airway.
- Signs of Respiratory Distress:
- Tachypnea: Increased respiratory rate.
- Difficulty breathing, especially during inspiration
- Retractions: Indrawing of the suprasternal notch, intercostal spaces, and epigastrium.
- Nasal Flaring: Common in pediatric patients.
- Posture: Patients may lean forward (tripod position) to maximize airway diameter (especially in epiglottitis).
- Voice Changes: Hoarseness (laryngeal origin) or "muffled" voice (supraglottic/pharyngeal origin).
- Cyanosis (late sign)
5. Paraclinical and Radiological Examinations
Clinical.- Observe breathing pattern
- Endoscopy: Flexible fiberoptic laryngoscopy is the gold standard for visualising the site of obstruction.
- Pulmonary function tests (after acute phase): Flattened inspiratory loop → extrathoracic obstruction
- Imaging:
- Lateral Neck X-ray: To look for the "Thumb sign" (epiglottitis) or retropharyngeal thickening.
- AP Neck X-ray: To look for the "Steeple sign" (subglottic narrowing in Croup).
- CT/MRI: For chronic cases or suspected neoplasms to assess tumor extent.
- Laboratory: Arterial Blood Gas (ABG) (hypoxia and hypercapnia).
6. Treatment Options
- Emergency Management:
- Oxygen therapy: High-flow O2 (or Heliox to reduce turbulence).
- Corticosteroids: IV Dexamethasone to reduce mucosal edema.
- Adrenaline: Nebulized racemic epinephrine for temporary shrinkage of mucosa.
- Surgical Intervention:
- Endotracheal Intubation: Difficult in cases of anatomical distortion.
- Tracheostomy: Indicated if intubation fails or for long-term airway management.