Trigeminal nerve - anatomy, physiology, examination, syndromes
Anatomy
The trigeminal nerve (CN V) is the largest cranial nerve and is a mixed nerve with sensory and motor functions.
Divisions
V1 – Ophthalmic Division (Sensory)
Supplies: Forehead. Scalp. Upper eyelid. Cornea. Dorsum of nose
V2 – Maxillary Division (Sensory)
Supplies: Cheek. Upper lip. Upper teeth. Nasal cavity. Palate
V3 – Mandibular Division (Mixed)
Sensory: Lower lip.Chin. Lower teeth. Anterior 2/3 of tongue (general sensation)
Motor:
- Muscles of mastication: Masseter. TemporalisM edial pterygoid. Lateral pterygoid
Physiology
Sensory Functions: Touch. Pain. Temperature. Proprioception from the face. Corneal sensation
Motor Functions: Mastication (chewing). Jaw movements
Reflexes
Corneal Reflex
- Afferent: CN V1. Efferent: CN VII
- Response: bilateral blinking
Jaw Jerk Reflex
- Afferent and efferent: CN V
- Normally absent or minimal
Examination
1. Sensory Examination
- Test bilaterally in all three divisions: Light touch. Pain (pinprick). Temperature (if necessary)
- Compare: V1, V2, and V3 territories
2. Corneal Reflex: Touch the cornea gently with cotton.
- Normal response: Bilateral eyelid closure
3. Motor Examination
Inspection
- Look for: Temporal wasting. Masseter wasting. Palpation. Ask the patient to clench their teeth.
Palpate: Masseter muscles. Temporalis muscles. Jaw Movement
- Ask the patient to: Open mouth. Move jaw side to side
Trigeminal Nerve Syndromes
1.Trigeminal Neuropathy
- Features: Facial numbness.,Reduced facial sensation. Weakness of mastication. Reduced corneal reflex
- Causes: Tumors. Trauma. Multiple sclerosis
2.Trigeminal Neuralgia (Tic Douloureux): Most common trigeminal disorder.
- Clinical Features: Sudden severe unilateral facial pain. Electric shock-like attacks. Lasts seconds to minutes
- Triggered by: Chewing. Talking. Brushing teeth. Touching the face
- Most commonly affects: V2 and V3 divisions
3.Motor Trigeminal Lesion
- Features: Weakness of mastication muscles.Jaw deviates toward the affected side on opening. Muscle atrophy
- Reason: Unopposed action of the normal pterygoid muscle.
4.Lesion of the Main Sensory Nucleus
- Features: Ipsilateral loss of facial sensation. Reduced corneal reflex