Nuclear Medicine · MU Sofia

7. Normal tissue and organ radiosensitivity. Early and late radiation reactions.

Covers the factors weighed when prescribing a radiotherapy dose, including patient status, treatment goal, tumour nature and practical constraints. Introduces intensity-modulated radiation therapy, explaining how CT or MRI planning shapes the dose to the tumour while sparing healthy tissue, and lists the malignancies where it is most widely used, such as prostate, head and neck, CNS and breast.

Inside: 1 section · 9 flashcards · 1 min

Topic 22 of 50 in the MU Sofia syllabus for Nuclear Medicine (Medicine, Year 4). The free AceMed note covers it in 1 section, about 117 words (1 min of reading), with 9 flashcards.

In this note

  1. Main algorithms for prescribing and delivering radiotherapy

Main algorithms for prescribing and delivering radiotherapy

When considering the dose of radiotherapy take into account the patient status (age, health etc), the goal (e.g. is it curative, neoadjunctive etc), the nature of the cancer, and the practical restrains of delivering radiotherapy.

Intensity-modulated radiation therapy (IMRT) is an accepted method for radiation treatment to provide a prescribed and uniform dose to the target volume and minimum dose to normal tissues.

Treatment is planned with CT or MRI to computerize the dose based on the tumor shape and structure. IMRT allows higher doses to be delivered to the cancer without the additional damage of healthy cells. IMRT is most extensively used to treat prostate, head and neck, CNS, breast, thyroid, lung, GI and other malignancies.

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