Topic 40
= more common than artery occlusion; typically in 60 or above men
Causes
- Sclerotic retinal artery putting pressure on the vein
- Hyperviscosity of blood (polycythemia,hyperlipidemia&maccroglobulinemia)
- Periphlebitis retinae Raised IOP (thus more common in open-angle glaucoma)
- Local causes (orbital cellulitis , facial erysipelas& cavernous sinus thrombosis )
- Classification :it may affect Central retinal vein (non-ischaemic or ischaemic) or branch retinal vein
Central retinal vein occlusion
1. Non-ischaemic CRVO
(More common than Ischaemic; 75%) aka venous stasis retinopathy
- Mild to moderate loss vision
- Early cases → mid venous congestion with many twists & turns + a few flame-shaped haemorrhages more in periphery , mild/no macular oedema +mild papilloedema
- late stages → sheath formation around the main veins & cilioretinal collateral around the disc with partially absorbed retinal haemorrhages chronic cystoid oedema
- Treatment : usually not required with 50% gain normal vision Visual loss in patients is due to chronic cystoid macular oedema
2. Ischaemic CRVO (haemorrhagic retinopathy)
- Sudden complete occlusion of central retinal vein with sudden visual loss
- Early→ massive engorgement ,congestion + twist & turn of retinal veins + massive haemorrhage giving splashed tomato appearance ,+ many soft exudate + papilloedema Macular area is full of haemorrhages and severely oedematous
- Late : sheath formation around veins +collaterals around disc , neovascularisation at disc/periphery , macula→ obvious pigmentary changes + chronic cystoid oedema Complications: neovascular glaucoma 50%, Rubeosis iridis, sometimes Vitreous haemorrhage and proliferative retinopathy Treatment: Panretinal photocoagulation after intraretinal blood is absorbed
Differential CRVO: visual field defect & relative afferent pupillary defect
Branch retinal vein occlusion: more common than central vein occlusion
- At main branch at disc margin causing hemispheric occlusion, major branch away from disk at A-V crossing → quadrantic occlusion and small macular or peripheral branch occ.
- Oedema& haemorrhage limited to area; vision defects if macular is involved Complications: chronic macular oedema &neovasc.,
- treatment: grid/scatter photocoagulation