Medicine · Year 3 · MU Sofia

General Pathology

The full MU Sofia syllabus for General Pathology, Medicine, Year 3: 46 topics, every one with a free study note (2 hours of reading), and 651 flashcards. Updated 9 November 2026.

syllabus topics: 46
free notes: 46
flashcards: 651
of reading: 2 h

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Syllabus

The topics in the order of the MU Sofia syllabus. Each one with a note opens in AceMed once you're signed in.

1. General and Special Pathology objectives. Basic terminology, purpose, tasks, methods.2 min · 15 cards
2. Cellular injury; common causes and mechanisms.2 min · 12 cards
3. Reversible cell injury due to compromised ionic transfer (cellular swelling): granular degeneration, vacuolar degeneration, hydropic change.2 min · 14 cards
4. Lipid accumulations in parenchymal and stromal cells. Lipid phagocytosis.2 min · 9 cards
5. Complex lipid accumulations: lipidoses.1 min · 11 cards
6. Abnormal intracellular glycogen accumulations. Glycogenoses.2 min · 15 cards
7. Hemoglobin-derived pigment accumulations. Hemosiderosis. Types of jaundice.3 min · 16 cards
8. Non-hemoglobin-derived pigment accumulations: melanin, lipofuscin.2 min · 13 cards
9. Exogenous pigments – types, organ sites.1 min · 13 cards
10. Extracellular accumulations: hyalinosis; fibrinoid swelling.3 min · 14 cards
11. Extracellular accumulations: amyloidosis. Types of amyloidosis, pathogenesis, microscopic & gross organ pathomorphology. Histochemical staining methods.3 min · 15 cards
12. Extracellular accumulations of calcium and uric acid salts.1 min · 11 cards
13. Metabolic and structural abnormalities of collagen, elastin and proteoglycans. Mucopolysaccharidoses.5 min · 16 cards
14. Irreversible cell injury – cell death. Types of necrosis; microscopic & gross pathomorphology. Apoptosis.8 min · 15 cards
15. Ischemic necrosis – infarction. Morphogenesis. Types of infarctions – anemic, hemorrhagic. Organ sites. Microscopic & gross pathomorphology.2 min · 16 cards
16. Clinico-anatomical types of necrosis: gangrene, decubitus, sequestration.2 min · 15 cards
17. Hemorrhages – types, pathogenesis; denomination according to organ site.2 min · 15 cards
18. Hemodynamic disorders. Arterial hyperemia. Venous congestion – systemic and organ-specific.4 min · 16 cards
19. Systemic hemodynamic disorders – peripheral tissue hypoperfusion (shock). DIC syndrome.5 min · 16 cards
20. Thrombosis. Pathogenesis, thrombus morphology, types. Outcome of thrombosis.2 min · 15 cards
21. Embolism – arterial and venous; types, sites of origin, target organs.4 min · 16 cards
22. Edema – types, pathogenesis and pathomorphology according to organ site.2 min · 15 cards
23. Inflammation. Definition, etiology, pathogenesis, types.1 min · 14 cards
24. Inflammation. Inflammatory mediators.5 min · 14 cards
25. Acute inflammation. Morphologic patterns of acute inflammation, types of inflammatory cells, tissue alterations.2 min · 14 cards
26. Chronic inflammation. Etiology, types, morphology.1 min · 13 cards
27. Specific inflammation in rheumatism, tuberculosis, sarcoidosis, syphilis. Histological characteristics of granulomas.3 min · 15 cards
28. Specific inflammation in leprosy, typhoid enteritis, mycoses and parasitic infections. Microscopic & gross pathomorphology of organ site alterations.2 min · 16 cards
29. Immunity. Types of immunity. Pathological immune reactions. Pathomorphology.6 min · 14 cards
30. Transplantation immunity. Rejection of tissue transplants.3 min · 15 cards
31. Regeneration and repair: types of physiologic renewal and posttraumatic repair in different cells and organs.2 min · 13 cards
32. Regeneration and repair: wound and bone healing. Stages of the reparative process.2 min · 14 cards
33. Adaptations: hypertrophy, hyperplasia and metaplasia. Microscopic & gross pathomorphology.1 min · 14 cards
34. Adaptations: atrophy. Types of atrophy. Microscopic & gross pathomorphology.1 min · 14 cards
35. Neoplasia: etiology, pathogenesis, classification and nomenclature.2 min · 15 cards
36. Neoplastic growth, histogenesis and structure characteristics. Precancer. General histological features of benign, malignant; epithelial and mesenchyme tumors.4 min · 15 cards
37. Connective tissue benign & malignant neoplasms. Microscopic & gross pathomorphology.1 min · 12 cards
38. Benign & malignant neoplasms of smooth and striated muscle. Microscopic & gross pathomorphology.1 min · 14 cards
39. Benign & malignant neoplasms of vessel walls.1 min · 15 cards
40. Osteogenic sarcoma. Malignant synovioma. Anatomic sites, microscopic & gross pathomorphology.1 min · 13 cards
41. Benign & malignant neoplasms originating from melanocytes. Anatomic sites, microscopic & gross pathomorphology.1 min · 14 cards
42. Teratogenous neoplasms – teratomas and teratocarcinomas. Anatomic sites, microscopic & gross pathomorphology.1 min · 14 cards
43. Congenital anomalies. Classification. Exogenous and endogenous teratogens.1 min · 13 cards
44. Gene mutations. Chromosomal syndromes and diseases. Blastopathies – double malformations.2 min · 16 cards
45. Embryopathies. Cardiovascular system malformations.2 min · 12 cards
46. Embryopathies. Malformations of central nervous system and limbs.3 min · 15 cards

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