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Medicine · Year 3 · MU Plovdiv

Pathophysiology

The full MU Plovdiv syllabus for Pathophysiology, Medicine, Year 3: 63 topics, 24 topics with a free study note (2 hours of reading), and 500 flashcards. Updated 10 November 2026.

syllabus topics
63
free notes
24
flashcards
500
of reading
2 h
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Syllabus

The topics in the order of the MU Plovdiv syllabus. Each one with a note opens in AceMed once you're signed in.

  1. 1. Health and disease, contemporary view of disease. Pathologic reactions, processes and conditions. General etiology and pathogenesis.Being written
  2. 2. Reactivity and resistance. Factors, influencing reactivity and resistance. Types of reactivity and resistance.Being written
  3. 3. Hypersensitivity reactions – types, pathogenesis. Anaphylaxis.Being written
  4. 4. Autoimmune diseases and immunodeficient states.Being written
  5. 5. Disturbances in peripheral circulation – arterial and venous hyperemia, ischaemia, infarction.15. Ischemic necrosis – infarction. Morphogenesis. Types of infarctions – anemic, hemorrhagic. Organ sites. Microscopic & gross pathomorphology. · 18. Hemodynamic disorders. Arterial hyperemia. Venous congestion – systemic and organ-specific.6 min · 32 cards
  6. 6. Disturbances in peripheral circulation – thrombosis and embolism.20. Thrombosis. Pathogenesis, thrombus morphology, types. Outcome of thrombosis. · 21. Embolism – arterial and venous; types, sites of origin, target organs.6 min · 31 cards
  7. 7. Changes in blood glucose levels – hyperglycemic and hypoglycemic states.Being written
  8. 8. Diabetes mellitus – etiology, pathogenesis, pathophysiology of major symptoms.58 & 59. Diabetes mellitus - etiology, pathogenesis & complication4 min · 15 cards
  9. 9. Diabetes mellitus – pathobiochemistry – alterations in carbohydrate, protein and lipid metabolism. Mechanisms of development of the acute and chronic complications.Being written
  10. 10. Dyslipidemias – types. Atherosclerosis – risk factors, etiology, pathogenesis, consequences and complications.47. Atherosclerosis. Etiology, pathogenesis and general characteristics of atherosclerotic vessel alterations. · 77. Dyslipidemia6 min · 30 cards
  11. 11. Obesity – definition, types, pathogenesis, complications. Metabolic syndrome.76. Obesity and Metabolic syndrome2 min · 11 cards
  12. 12. Changes in plasma protein levels. Disturbances in aminoacid metabolism.Being written
  13. 13. Disturbances in the end-stage protein metabolism – hyperazotemias. Disturbances in purine metabolism – pathophysiology of gout and its complications.Being written
  14. 14. Disturbances in water-electrolyte balance – dehydration and hyperhydration. Types and complications.Being written
  15. 15. Edemas – definition, factors for edema formation. Types of edemas.22. Edema – types, pathogenesis and pathomorphology according to organ site.2 min · 15 cards
  16. 16. Disturbances in mineral metabolism (Ca, P, Mg). Pathophysiology of osteoporosis and osteomalacia.Being written
  17. 17. Disturbances in acid-base balance – general characteristics, regulation, parameters, compensations. Respiratory and metabolic acidosis.Being written
  18. 18. Disturbances in acid-base balance – general characteristics, regulation, parameters, compensations. Respiratory and metabolic alkalosis.Being written
  19. 19. Hypoxia – definition, parameters. Pathogenetic classification of hypoxias. Characteristics of hypoxic hypoxias.Being written
  20. 20. Hypoxia – definition, parameters. Pathogenetic classification of hypoxias. Characteristics of non-hypoxic hypoxias.Being written
  21. 21. Adaptations to hypoxia at cellular, tissue and organ level (HIFs). Main principles and mechanisms.Being written
  22. 22. Inflammation – definition and biological significance. Classification and outcomes of inflammation. Cardinal signs of inflammation.23. Inflammation. Definition, etiology, pathogenesis, types.1 min · 14 cards
  23. 23. Inflammation – stages. Mediators. Vascular changes. Cellular response. Alterations in metabolism.24. Inflammation. Inflammatory mediators. · 25. Acute inflammation. Morphologic patterns of acute inflammation, types of inflammatory cells, tissue alterations.7 min · 28 cards
  24. 24. Disturbances in body temperature regulation – hypo- and hypertermia.Being written
  25. 25. Fever – definition, etiology and pathogenesis. Significance of fever. Stages of fever. Changes in metabolism in fever. Alterations in the function of organs and systems.Being written
  26. 26. Neoplasms – general characteristic and etiology. Definition and stages of carcinogenesis.35. Neoplasia: etiology, pathogenesis, classification and nomenclature.2 min · 15 cards
  27. 27. Neoplasms – tumor/organism interactions. Paraneoplastic syndromes.Being written
  28. 28. Functional pulmonary diagnostics – spirometry, diffusion capacity, lung volumes, bodyplethysmography, cardio-pulmonary exercise tests.Being written
  29. 29. Basic mechanisms disturbing lung function – obstruction of the airflow in the airways – types. Main pathogenetic mechanisms, causing obstruction – bronchial inflammation, bronchial hyperresponsiveness, alveolo-capillary and bronchiolar destruction.Being written
  30. 30. Obstructive disorders. Pulmonary hyperinflation. Disturbed functional capacity. COPD and bronchial asthma.2. Chronic obstructive pulmonary disease (COPD); · 4.Bronchial asthma11 min · 27 cards
  31. 31. Basic mechanisms disturbing lung function – types of restrictive ventilatory disorders. Main pathogenetic mechanisms, causing restriction – inflammation, fibrosis, edema, reduction of lung parenchyma, pleural and rib-cage dysfunctionalities.Being written
  32. 32. Restrictive disorders. Etiology and pathogenesis of pulmonary edema, pneumothorax, pneumonia and interstitial lung disease.Being written
  33. 33. Mechanisms responsible for disturbed gas exchange. Changes in the V/Q ratio, disturbed diffusion of gases through the alveolo-capillary barrier, alveolar hypoventilation syndrome, disturbances in respiratory control.Being written
  34. 34. Acute respiratory failure – etiology, pathogenesis, types.11. Acute and chronic respiratory failure;3 min · 15 cards
  35. 35. Chronic respiratory failure – etiology, pathogenesis, types, adaptations, complications.11. Acute and chronic respiratory failure;3 min · 15 cards
  36. 36. Coronary artery disease – definition, types, pathogenesis.Being written
  37. 37. Arterial hypertensions – essential hypertension. Etiology, pathogenesis. Secondary (symptomatic) hypertensions.34. Arterial Hypertension – etiology, classification, clinical features, complications · 23. Arterial hypertension19 min · 29 cards
  38. 38. Hypotension, colapse and syncope. Acute insufficiency of hemodynamics – shock – definition, types, etiology, pathogenesis.14. Shock and Circulatory Failure4 min · 13 cards
  39. 39. Heart failure - definition, etiology, pathogenesis and types. Compensatory mechanisms.23. Chronic congestive heart failure – etiology, pathogenesis, clinical features. · 13. Acute and chronic heart failure;17 min · 31 cards
  40. 40. Functional signs of heart failure.13. Acute and chronic heart failure;4 min · 15 cards
  41. 41. Pathogenesis of some complex symptoms. Dyspnea and fatigue.Being written
  42. 42. Anemias – definition and classification. Posthemorrhagic anemias.Being written
  43. 43. Anemias due to disturbed hemopoiesis. Anemias due to increased hemolysis.Being written
  44. 44. Leukemias – definition, etiology, pathogenesis, types.Being written
  45. 45. Disorders of hemostasis (hemorrhagic diateses).71. Hemorrhagic diathesis – normal hemostasis. Thrombocytopenia – · 72. Hemorrhagic diathesis – normal hemostasis. Hemophilia5 min · 30 cards
  46. 46. Disorders of hemostasis (thrombotic diateses). DIC – syndrome.Being written
  47. 47. Disorders in the gastrointestinal system. Gastritis – etiology and pathogenesis. Peptic ulcer disease – etiology and pathogenesis.75. Acute and chronic gastritis – etiology, pathogenesis, types; microscopic & gross pathomorphology. · 92. Peptic ulcer8 min · 29 cards
  48. 48. Pancreatitis – types, etiology, pathogenesis, complications. Disorders in the gastrointestinal system: intestinal obstruction (ileus), gastro-intestinal autointoxication. Disorders in the intestinal microbiome.Being written
  49. 49. Basic etiology and pathogenesis of liver diseases. Hepatitis.Being written
  50. 50. Functional signs of liver damage – jaundice, portal hypertension, ascites, anemia, hepato-renal and hepato-pulmonary syndromes. Disturbances in hemostasis.88. Portal hypertension – pathogenesis, vascular and organ-specific manifestations, complications. · 106. Cholestasis /jaundice syndrome/6 min · 27 cards
  51. 51. Pathogenesis of liver cirrhosis. Hepatic encephalopathy.100. Liver cirrhosis – etiology, pathogenesis, clinical features · 40. Liver failure - hepatic encephalopathy and coma6 min · 28 cards
  52. 52. Basic etiology and pathogenesis of renal disorders. Urinary syndrome, alterations in diuresis. Nephritic and nephrotic syndromes.Being written
  53. 53. Etiology and pathogenesis of acute renal failure. Complications.26. Acute renal failure3 min · 14 cards
  54. 54. Etiology and pathogenesis of chronic renal failure.27. Chronic renal failure3 min · 14 cards
  55. 55. Functional manifestations of renal disorders – edemas, hypertension, anemia, renal osteodystrophy, hemostatic disturbances, polyserositis, disturbances in acid-base and water- electrolyte balance. Uremia and uremic encephalopathy.Being written
  56. 56. Basic etiology and pathogenesis of endocrine disorders.Being written
  57. 57. Disturbances in the function of the pituitary gland.Being written
  58. 58. Disturbances in the function of the thyroid gland.Being written
  59. 59. Disturbances in the function of the suprarenal glands. Disturbances in the functions of the gonads.Being written
  60. 60. Basic etiology and pathogenesis of the diseases of the nervous system. – cerebral ischemia, cerebral edema, intracranial hypertension, neurodegenerative diseases.Being written
  61. 61. Disorders in sleep and wakefulness – insomnia.Being written
  62. 62. Disorders in sleep and wakefulness – central and obstructive sleep apnea.12. Sleep Apnea3 min · 12 cards
  63. 63. Pain – definition, types and pathophysiology.84. Physiology of pain. Primary and secondary pain. Visceral pain. Antinociceptive system.6 min · 10 cards

Pathophysiology at other universities

  • MU Sofia, Medicine168 notes

Other Year 3 subjects

  • Clinical Laboratory2 notes
  • Hygiene and Ecology76 notes
  • Microbiology49 notes
  • Occupational Diseases and Toxicology13 notes
  • Pathological Anatomy and Cytopathology130 notes
  • Pharmacology and Clinical Pharmacology57 notes
  • Propaedeutics of Internal Diseases96 notes
  • Roentgenology and Radiology14 notes

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